Results 81 to 90 of about 791,515 (297)

Anomaly Detection in Software-Defined Networking Using Machine Learning

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2019
In recent years, the Software-Defined Networking (SDN) approach has emerged that aims to make computernetworks more flexible. Although the SDN application on Google's internal network demonstrates the usefulnessof the Software-Defined Network approach ...
Soumaine Bouba Mahamat, Celal Çeken
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Fast Recovery in Software-Defined Networks

2014 Third European Workshop on Software Defined Networks, 2014
Although Software-Defined Networking and its implementation OpenFlow facilitate managing networks and enable dynamic network configuration, recovering from network failures in a timely manner remains non-trivial. The process of (a) detecting the failure, (b) communicating it to the controller and (c) recomputing the new shortest paths may result in an ...
Van Adrichem, N.L.M. (author), Van Asten, B.J. (author), Kuipers, F.A. (author)   +2 more
openaire   +4 more sources

A Survey of Controller Placement Problem in Software-Defined Networking

IEEE Access, 2019
In order to simplify the management of the traditional network, software-defined networking (SDN) has been proposed as a promising paradigm shift that decouples control plane and data plane, providing programmability to configure the network.
Jie Lu, Zhen Zhang, Tao Hu, P. Yi, Julong Lan   +4 more
semanticscholar   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Flexible open network operating system architecture for implementing higher scalability using disaggregated software‐defined optical networking

IET Networks
The enhanced capacity of optical networks is a significant advantage within the global telecommunications industry. Optical networks provides transmission of information over large distances with reduced latency. However, the growing intricacy of network
Kenneth Nsafoa‐Yeboah, Eric Tutu Tchao, Benjamin Kommey, Andrew Selasi Agbemenu, Griffith Selorm Klogo, Nana Kwadwo Akrasi‐Mensah   +5 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

A Survey of Networking Applications Applying the Software Defined Networking Concept Based on Machine Learning

IEEE Access, 2019
The main task of future networks is to build, as much as possible, intelligent networking architectures for intellectualization, activation, and customization.
Yanling Zhao, Ye Li, Xinchang Zhang, Guanggang Geng, Wei Zhang, Yanjie Sun   +5 more
semanticscholar   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Software-defined Networking-based DDoS Defense Mechanisms

ACM Computing Surveys, 2019
Distributed Denial of Service attack (DDoS) is recognized to be one of the most catastrophic attacks against various digital communication entities.
Rochak Swami, M. Dave, V. Ranga
semanticscholar   +1 more source