Results 31 to 40 of about 27,771 (227)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Benefits, Security and Issues in Software Defined Networking (SDN)

NUST Journal of Engineering Sciences, 2016
Applications used now a day are bandwidth hungry like Online Shopping, IPTV, E-Commerce and many other which require more and more bandwidth as well as continuous bandwidth.
Nasir Shahzad, Ghulam Mujtaba, Manzoor Elahi   +2 more
doaj   +1 more source

Software Defined Networking for community network testbeds [PDF]

2013 IEEE 9th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob), 2013
Wireless Community Networks have received increasing attention the latest years. In an effort to set the cornerstone for an internet without central authorities and monopolies, network engineers throughout the world have started creating community networks.
Dimogerontakis, Emmanouil, Vilalta, Ivan, Navarro Moldes, Leandro   +2 more
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Software defined networking firewall for industry 4.0 manufacturing systems

Journal of Industrial Engineering and Management, 2018
Purpose: In order to leverage automation control data, Industry 4.0 manufacturing systems require industrial devices to be connected to the network.
Akihiro Tsuchiya, Francisco Fraile, Ichiro Koshijima, Angel Ortiz, Raul Poler   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

FCR: Fast and Consistent Controller-Replication in Software Defined Networking

IEEE Access, 2019
We consider the problem of coordination among replicated SDN controllers, where the challenge is to ensure a consistent view of the network while reacting to network events in a prompt manner.
Maaz Mohiuddin, Mia Primorac, Eleni Stai, Jean-Yves Le Boudec   +3 more
doaj   +1 more source

Wireless Mesh Software Defined Networks (wmSDN) [PDF]

2013 IEEE 9th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob), 2013
In this paper we propose to integrate Software Defined Networking (SDN) principles in Wireless Mesh Networks (WMN) formed by OpenFlow switches. The use of a centralized network controller and the ability to setup arbitrary paths for data flows make SDN a handy tool to deploy fine-grained traffic engineering algorithms in WMNs.
DETTI, ANDREA, Pisa, C, SALSANO, STEFANO DOMENICO, BLEFARI MELAZZI, NICOLA   +3 more
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Industrial Networks Driven by SDN Technology for Dynamic Fast Resilience

Information, 2021
Software-Defined Networking (SDN) provides the prospect of logically centralized management in industrial networks and simplified programming among devices.
Nteziriza Nkerabahizi Josbert, Wang Ping, Min Wei, Yong Li   +3 more
doaj   +1 more source