Results 91 to 100 of about 1,455,623 (376)

STCS: Spatial-Temporal Collaborative Sampling in Flow-Aware Software Defined Networks

open access: yesIEEE Journal on Selected Areas in Communications, 2020
General traffic analysis based on deep packet inspection (DPI) techniques at switches cannot grasp the detailed knowledge of network applications going into internal switches, and the statistics-based reports of switches lack flow-level recognition of ...
Xiaofei Wang   +4 more
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Quantum-Aware Software Defined Networks [PDF]

open access: yes, 2016
Software Defined Networks (SDN) represent a major paradigm change in communications networks. It provides a level of abstraction and independence from the traditional networking practice that allows for a fast path of innovation and, specifically, opens ...
Aguado, Alejandro   +11 more
core   +1 more source

Towards Dynamic Controller Placement in Software Defined Vehicular Networks

open access: yesSensors, 2020
The emerging SDVN (Software Defined Vehicular Network) paradigm promises to bring flexibility and efficient resource utilization to vehicular networks, enabling the emergence of novel Intelligent Transportation Services.
Soufian Toufga   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

A Novel Software-Defined Convolutional Neural Networks Accelerator

open access: yesIEEE Access, 2019
The convolutional neural network (CNN) has been widely applied in computer vision applications. Due to the intensive computation, the general central processing unit (CPU) processors are not efficient to meet the real-time requirement.
Yufeng Li, Yankang Du
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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