Generic types as design patterns for planning domain specifications
In this paper we investigate the use of ‘Generic Types’ as design patterns to assist in the specification of planning domains. Current planning technology uses induced patterns discovered in a domain specification to speed up plan creation. We argue that
McCluskey, T.L. +3 more
core
Post-Diagnostic Lifestyle Adaptations in Fibromyalgia: A Network and Cluster Analysis of Real-World Behavioral Patterns. [PDF]
NutrientsKosiorz M +3 more
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Semantic discovery and reuse of business process patterns
, 2010 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In modern organisations business process modelling has become fundamental due to the increasing rate of organisational change.
Aldin, Laden
core
Impact of virtual threads and garbage collection on energy efficiency of Java applications for battery powered IoT devices. [PDF]
Sci RepShanjai Kumar S +4 more
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Assessing Interstimulus Interval and Waveform Effects on Vibrotactile Pattern Recognition on the Forearm for Transfemoral Prosthetic Sensory Feedback. [PDF]
Sensors (Basel)Karimi M +4 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
From pilots to platforms: making digital health work for chronic disease management. [PDF]
Front Public HealthLee DY +7 more
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source