Results 231 to 240 of about 6,721,355 (335)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Synthetic datasets for open software development in rare disease research. [PDF]

Orphanet J Rare Dis
Al-Dhamari I, Abu Attieh H, Prasser F.
europepmc   +1 more source

Software development process of Neotree - a data capture and decision support system to improve newborn healthcare in low-resource settings. [PDF]

Wellcome Open Res, 2022
Khan N, Crehan C, Hull-Bailey T, Normand C, Larsson L, Nkhoma D, Chiyaka T, Fitzgerald F, Kesler E, Gannon H, Kostkova P, Wilson E, Giaccone M, Krige D, Baradza M, Silksmith D, Neal S, Chimhuya S, Chiume M, Sassoon Y, Heys M.   +20 more
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Glottis Recognition Software Development Using Artificial Intelligence. [PDF]

Cureus
Masumori Y, Inoue S, Seino Y, Konishi M, Nishikawa H.   +4 more
europepmc   +1 more source

Automated conversion of Millennium-120 VMAT plans to HDMLC geometry: Software development and treatment of first patients. [PDF]

J Appl Clin Med Phys, 2022
Yang R, Lamey M, Bartha L, Johnston M, Warburton A, Gillund D, Becker N.   +6 more
europepmc   +1 more source

A Report on Recent Developments in Computing, Processor, and Software Research for High-Energy Physics: A Symposium Held in Guanajuato, Mexico May 8-11, 1984 [PDF]

, 1984
Thomas H. Nash
openalex  

A framework for the development and assurance of high integrity software

, 1994
Dolores R Wallace, Laura M Ippolito
openalex   +1 more source

Integration of usability issues within initial software development education. (It's all about the user dummy!) [PDF]

, 1999
Xris Faulkner, Fintan Culwin
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source