Results 241 to 250 of about 6,869,870 (334)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Glottis Recognition Software Development Using Artificial Intelligence. [PDF]

Cureus
Masumori Y, Inoue S, Seino Y, Konishi M, Nishikawa H.   +4 more
europepmc   +1 more source

Software development process of Neotree - a data capture and decision support system to improve newborn healthcare in low-resource settings. [PDF]

Wellcome Open Res, 2022
Khan N, Crehan C, Hull-Bailey T, Normand C, Larsson L, Nkhoma D, Chiyaka T, Fitzgerald F, Kesler E, Gannon H, Kostkova P, Wilson E, Giaccone M, Krige D, Baradza M, Silksmith D, Neal S, Chimhuya S, Chiume M, Sassoon Y, Heys M.   +20 more
europepmc   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

A case study in statistical software development for advanced evidence synthesis: the combined value of analysts and research software engineers. [PDF]

BMC Med Res Methodol
Bradbury N, Morris T, Nevill C, Nevill J, Field R, Freeman S, Cooper N, Sutton A.   +7 more
europepmc   +1 more source

Integration of usability issues within initial software development education. (It's all about the user dummy!) [PDF]

, 1999
Xris Faulkner, Fintan Culwin
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Experiences with criticality predictions in software development [PDF]

, 1997
Christof Ebert
openalex   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Developing a Mobile App to Prevent Suicide Based on a Software Development Life Cycle: Application of Ecological Momentary Assessment and Interventions. [PDF]

Int J Ment Health Nurs
Jeong H, Kim H, Jeon Y, Kim H.
europepmc   +1 more source