Results 201 to 210 of about 4,581,706 (333)

An analysis method for improving a bug modification process in open source software development [PDF]

, 2009
Akinori Ihara, Masao Ohira, Kenichi Matsumoto   +2 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

LocSys: A Low-Code Paradigm for the Development of Cyber-Physical Applications. [PDF]

Sensors (Basel)
Panayiotou K, Tsardoulias E, Symeonidis AL.   +2 more
europepmc   +1 more source

The software configuration management system for image processing algorithm development

, 2005
Jeongheon Lee, Oksam Chae
openalex   +2 more sources

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

SynergyBug: A deep learning approach to autonomous debugging and code remediation. [PDF]

Sci Rep
Chen H.
europepmc   +1 more source

An Examination of the Use of Open Source Software Processes as a Global Software Development Solution for Commercial Software Engineering [PDF]

, 2009
Gary Gaughan, Brian Fitzgerald, Maha Shaikh   +2 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Development of the Psychosocial Rehabilitation Web Application (Psychosocial Rehab App). [PDF]

Nurs Rep
Cirino Campos FAA, Sánches García JC, Galdino da Silva GL, Araújo JAL, Farfán Ulloa I, Caritá EC, Feitosa FB, Moll MF, Rodriguez TDM, Ventura CAA.   +9 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source