Results 41 to 50 of about 1,753,525 (297)

Factors Models of Scrum Adoption in the Software Development Process: A Systematic Literature Review [PDF]

ReCIBE, 2018
(Background) The adoption of Agile Software Development (ASD), in particular Scrum, has grown significantly since its introduction in 2001. However, in Lima, many ASDs implementations have been not suitable (uncompleted or inconsistent), thus losing ...
Marilyn Sihuay, Abraham Dávila, Marcelo Pessoa   +2 more
doaj  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

A model-driving approach to constructing robotic systems

Journal of Computer Science and Technology, 2014
Most robotic systems tend to be complex to maintain and reuse because existing frameworks are based mainly on code-driven approaches. This means the software development process is reduced to the implementation of systems using specific programming ...
Claudia Pons, Gabriela Pérez, Roxana Silvia Giandini, Gabriel Alfredo Baum   +3 more
doaj  

The Process of Offshore Software Development [PDF]

, 2003
There are many studies of information technology outsourcing but very few discuss in depth the process of offshore software development outsourcing. The aim of this research is to understand the important issues and strategies in managing activities and, relationships among software development teams involved in offshore outsourcing. The study involves
Aini Aman, Brian Nicholson
openaire   +2 more sources

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

A tool for evaluation of the software development process [PDF]

Journal of Systems and Software, 2001
As part of their effort to reduce development time and improve the quality of their products, software developers are looking at the software development process they use. They reason that a high quality process is likely to lead to a high quality product.
Henderson, Peter, Howard, Yvonne Margaret, Walters, Robert John   +2 more
openaire   +3 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Using system dynamics to teach about dependencies, correlation and systemic thinking on the software process workflows

IET Software, 2021
It is important to count on tools to help software professionals to evaluate the software process and how it may be affected by factors related to its deployment.
German‐Lenin Dugarte‐Peña, María‐Isabel Sánchez‐Segura, Antonio deAmescua, Fuensanta Medina‐Domínguez, Stefano Armenia   +4 more
doaj   +1 more source