In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A software process engineering approach to improving software team productivity using socioeconomic mechanism design [PDF]
Software development involves teams of interconnected individuals who are encouraged to work collectively in a knowledge and communication network to produce software artifacts.
O'Connor, Rory +7 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Harnessing software development contexts to inform software process selection decisions [PDF]
Software development is a complex process for which numerous approaches have been suggested. However, no single approach to software development has been met with universal acceptance, which is not surprising, as there are many different software ...
Lichter, H. +15 more
core
DevOps Integration With Capability Model Maturity Integration: A Systematic Mapping Review
The Capability Maturity Model Integration (CMMI) is a framework for improving and optimizing organizational processes. DevOps is a revolutionary method that bridges the gap between software development and IT operations by encouraging cooperation and ...
Rania Rajab, Mouhib Alnoukari
doaj +1 more source
Factors Models of Scrum Adoption in the Software Development Process: A Systematic Literature Review [PDF]
(Background) The adoption of Agile Software Development (ASD), in particular Scrum, has grown significantly since its introduction in 2001. However, in Lima, many ASDs implementations have been not suitable (uncompleted or inconsistent), thus losing ...
Marilyn Sihuay +2 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
software testing process automation based on utp - a case study [PDF]
Chinese Acad Sci, Inst SoftwareAutomation of software testing process plays an important role in improving software quality, shortening period of development and reducing development cost.
Ying Q, Xue YZ, Zhao C, Chen W
core
Measuring Productivity in Agile Software Development Process: A Scoping Study [PDF]
An agile software development process is often claimed to increase productivity. However, productivity measurement in agile software development is little researched. Measures are not explicitly defined nor commonly agreed upon.
Shah, Syed +8 more
core +2 more sources

