Results 101 to 110 of about 5,323,332 (338)

Software engineering or methods for the multi-person construction of multi-version programs [PDF]

, 1975
David Lorge Parnas
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Relationship of software engineering and simulation [PDF]

, 1976
Elwood Baas, James Ellis
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Learning Software Engineering via Internet

E-learning and Education, 2005
In recent years, education authorities worldwide, including the German Federal Government, have invested heavily in the development of e-learning and multimedia materials for institutions of higher education.
Debora Weber-Wulff, Ilse Schmiedecke
doaj  

Interdisciplinary Approach to Software Engineering Education [PDF]

Journal of Systemics, Cybernetics and Informatics, 2009
One of the most serious problems in software engineering projects is the communication between users and developers. It is widely recognized that communication problems are a major factor in the delay and failure of software projects.
Alfred Schaetter, Hans-Georg Koeglmayr, Karlheinz Blankenbach, Markus Nippa   +3 more
doaj  

Registered reports in software engineering. [PDF]

Empir Softw Eng, 2023
Ernst NA, Baldassarre MT.
europepmc   +1 more source

Engineering processes in managing software system development [PDF]

, 1977
David Sung
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

S³EF-HBCAs: Secure and Sustainable Software Engineering Framework for Healthcare Blockchain Applications. [PDF]

Blockchain Healthc Today, 2023
Ramachandran M.
europepmc   +1 more source