Results 91 to 100 of about 8,130,795 (304)
Semantic Web Enabled Software Engineering
, 2014 Over the last decade, ontology has become an important modeling component in software engineering. Semantic Web Enabled Software Engineering presents some critical findings on opening a new direction of the research of Software Engineering, by exploiting
Pan, J.Z., Zhao, Y.
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Human and social factors of software engineering
, 2022 S.686Workshop Summary: From its initial days in the sixties and seventies, the field of software engineering has to a large extent been concerned with the technological aspects of software as well as the formal procedures to be followed and artifacts to ...
Maurer, F., Tessem, B., John, M.
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Software engineering, research software and requirements engineering. [PDF]
Softwaretechnik-TrendsResearch software is developed with aims and in contexts that differ from other software, by individuals who are often not trained software engineers. Furthermore, research software projects often suffer from resource scarcity, but produce artifacts that are crucial for research and require software engineering.
Druskat, Stephan +2 more
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Cyber Security and Software Engineering
Applied SciencesThe software engineering field faces significant challenges as cyber threats continue to evolve in sophistication and scale [...]
Young Lee, Jeong Yang
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
An engineering discipline of software: an Australian perspective [PDF]
, 1997 Engineering faculties within Australian universities are being asked to explore the feasibility of mounting separate Software Engineering programmes.
Armarego, J., Cohen, R.F.
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