Results 101 to 110 of about 1,132,150 (310)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Requirements Engineering: In Search of the Dependent Variables
, 2008 When software development teams modify their requirements engineering process as an independent variable, they often examine the implications of these process changes by assessing the quality of the products of the requirements engineering process,
Davis, Alan, Gorschek, Tony
core +1 more source
Beyond accuracy: Assessing software documentation quality
, 2020 Good software documentation encourages good software engineering, but the meaning of “good” documentation is vaguely defined in the software engineering literature.
ATAPATTU, Thushari +5 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Software engineering: Theory and practice
Journal of Computer Science and Technology, 2005 A book that describes and applies Software Engineering methods according to the state of the art of the subject matter; it is integrated with a proper exemplification and evolves as each topic is introduced. The material is designed for undergraduates of
Rodolfo Alfredo Bertone
doaj
Software developers' perceptions of soft skills in software requirements engineering [PDF]
Journal of Engineering Management and Competitiveness, 2018 Software requirements express users' needs and constraints for a software system to be constructed in order to solve some real problems. Both researchers and practitioners from industry point out that well performed requirements related activities have ...
Zorić Tamara, Stojanov Željko
doaj
An engineering discipline of software: an Australian perspective
, 1997 Engineering faculties within Australian universities are being asked to explore the feasibility of mounting separate Software Engineering programmes.
Armarego, J., Cohen, R.F.
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Putting the Engineering into Software Engineering Education [PDF]
IEEE Software, 2013 Based on over 20 years of teaching and research experience, the author provides his assessment of software engineering education. He then builds on the analysis to provide recommendations on how we need to diverge from computer science to increase our impact, gain credibility, and ultimately ensure the success and recognition of our young discipline. A
openaire +1 more source
Automotive Software Engineering in an increasingly Data-Driven Automotive Sector [PDF]
Automotive trends such as power-train electrification, personalization, connectivity, and automated driving are not well supported by the classical approach to hardware/software architectures that centre around numerous, dedicated electronic control ...
Westphal, Bernd +3 more
core +1 more source