Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Optimizing software engineering English translation using an enhanced Grey Wolf Optimization with self-attention and Bi-LSTM model. [PDF]
Yuan F, Liu Y, Ju Y, Abdalla AN.
europepmc +1 more source
Software engineering standards for epidemiological models. [PDF]
Horner JK, Symons JF.
europepmc +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
A laboratory experiment on using different financial-incentivization schemes in software-engineering experimentation. [PDF]
Bershadskyy D +6 more
europepmc +1 more source
Experimentation in software engineering: an introduction
C. Wohlin +5 more
semanticscholar +1 more source
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Editorial: Application of neuroscience in information systems and software engineering. [PDF]
Pryss R +5 more
europepmc +1 more source
The democratization of bioinformatics: A software engineering perspective. [PDF]
Lawlor B, Sleator RD.
europepmc +1 more source
Characteristics of mathematical modeling languages that facilitate model reuse in systems biology: a software engineering perspective. [PDF]
Schölzel C +3 more
europepmc +1 more source

