Results 61 to 70 of about 5,323,332 (338)
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Trends in Modern Exception Handling [PDF]
Computer Science, 2003 Exception handling is nowadays a necessary component of error proof information systems. The paper presents overview of techniques and models of exception handling, problems connected with them and potential solutions.
Marcin Kuta
doaj
IET Software, 2022 When following the principles of value‐based software engineering, business, customer satisfaction, and engineering considerations need to be balanced to develop and operate the software so that it satisfies the different stakeholders' expectations. This,
Philipp Haindl, Reinhold Plösch
doaj +1 more source
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Towards data-driven software engineering skills assessment [PDF]
International Journal of Crowd Science, 2018 Purpose - Today’s software engineers often work in teams to develop complex software systems. Therefore, successful software engineering in practice require team members to possess not only sound programming skills such as analysis, design, coding and ...
Jun Lin +4 more
doaj +1 more source
Open Science in Software Engineering [PDF]
Contemporary Empirical Methods in Software Engineering, 2019 Open science describes the movement of making any research artifact available to the public and includes, but is not limited to, open access, open data, and open source.
Daniel Méndez Fernández +3 more
semanticscholar +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase
FEBS Letters, EarlyView.The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu +5 more
wiley +1 more source
Automated issue assignment using topic modelling on Jira issue tracking data
IET Software, 2023 As more and more software teams use online issue tracking systems to collaborate on software projects, the accurate assignment of new issues to the most suitable contributors may have significant impact on the success of the project. As a result, several
Themistoklis Diamantopoulos +2 more
doaj +1 more source
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source