Results 61 to 70 of about 5,528,326 (333)
Competitive Approach to Information System Risk Analyses [PDF]
Computer Science, 2004 This article presents the method of IT risk assessment from human behaviour perspective, developed by the author. It is an alternative for the commonly used approaches to risk assessment, based on vulnerability and threat identification and the ...
Miroslaw Ryba
doaj
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Software Development Cost Estimation Methods [PDF]
Computer Science, 2003 Early estimation of project size and completion time is essential for successful project planning and tracking. Multiple methods have been proposed to estimate software size and cost parameters.
Bogdan Stepien
doaj
Documenting research software in engineering science
Scientific Reports, 2022 The reuse of research software needs good documentation, however, the documentation in particular is often criticized. Especially in non-IT specific disciplines, the lack of documentation is attributed to the lack of training, the lack of time or missing
Sibylle Hermann, Jörg Fehr
doaj +1 more source
An Empirical Study on Software Test Effort Estimation for Defense Projects
IEEE Access, 2022 Effort estimation of software testing plays a vital role in the effective completion of testing. In particular, software test effort estimation in defense projects is not an easy and simple phenomenon, owing to internal and external factors.
Esra Cibir, Tulin Ercelebi Ayyildiz
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Trends in Modern Exception Handling [PDF]
Computer Science, 2003 Exception handling is nowadays a necessary component of error proof information systems. The paper presents overview of techniques and models of exception handling, problems connected with them and potential solutions.
Marcin Kuta
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Navigating the Path of Women in Software Engineering: From Academia to Industry [PDF]
, 2023 Tatalina Oliveira +5 more
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source