Results 81 to 90 of about 1,625,789 (274)
A document-like software visualization method for effective cognition of c-based software systems [PDF]
, 2004 It is clear that maintenance is a crucial and very costly process in a software life cycle. Nowadays there are a lot of software systems particularly legacy systems that are always maintained from time to time as new requirements arise.
Sulaiman, Shahida
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A Software for Optimum Design of Laterally Loaded Bolted Joints
Gazi Üniversitesi Fen Bilimleri DergisiBolted joints, which are one of the detachable joining methods, are used extensively. The reliability of bolted joints is extremely important for the strength and life of the system.
Kadir Sarı, Hakan Dilipak
doaj +1 more source
Automatically Patching Vulnerabilities of Binary Programs via Code Transfer From Correct Versions
IEEE Access, 2019 The security of binary programs is significantly threatened by software vulnerabilities. When vulnerabilities are found, those applications are exposed to malicious attacks that exploit the known vulnerabilities.
Yikun Hu, Yuanyuan Zhang, Dawu Gu
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
InformaticsOpen-source software has experienced steady growth, driving increased research. However, open-source communities still need standardized processes to ensure software quality, and their characteristics make it challenging to adopt many usability ...
Lucrecia Llerena +3 more
doaj +1 more source
Modern Applied Science, 2011 In response to real and perceived short-comings in the quality and productivity of software engineering practices and projects, professionally-endorsed graduate and post-graduate curriculum guides have been developed to meet technical developments and evolving industry demands.
Caulfield, Craig +2 more
openaire +3 more sources
Software engineering and Ada in design [PDF]
Modern software engineering promises significant reductions in software costs and improvements in software quality. The Ada language is the focus for these software methodology and tool improvements.
Oneill, Don
core +1 more source
Report from GI-Dagstuhl Seminar 16394: Software Performance Engineering in the DevOps World [PDF]
, 2017 This report documents the program and the outcomes of GI-Dagstuhl Seminar 16394 "Software Performance Engineering in the DevOps World". The seminar addressed the problem of performance-aware DevOps.
Jamshidi, Pooyan +3 more
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source