Results 61 to 70 of about 387,273 (262)

Mathematical Modeling and Integration of Machine Learning-Based Prediction System on E-Learning Platform to Improve Students' Academic Performance

JTAM (Jurnal Teori dan Aplikasi Matematika)
The purpose of this study was to develop and integrate a student academic performance prediction system into an e-learning platform using a mathematical modelling approach combined with machine learning algorithms.
Anisatul Farida, Vihi Atina, Djatmiko Suwandi   +2 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

A Data-Driven Competency Detection Model for Improving Workforce Planning and Decision-Making

ITEGAM-JETIA
La transformación digital ha intensificado la necesidad de herramientas computacionales capaces de identificar competencias laborales emergentes en diferentes industrias.
Lucrecia Llerena, Nancy Rodriguez, Jefferson Bustamante, Angel Torres   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Review on Program Slicing Techniques towards Program Comprehension Application

Journal of Computing Research and Innovation, 2018
Presently, the software system has grown in size. One of the main challenges faced by programmers is to keep up with thousand or million lines of source code that needs to be read and understood.
Rozita Kadar, Naemah Abdul Wahab, Jamal Othman   +2 more
doaj  

A Software for Optimum Design of Laterally Loaded Bolted Joints

Gazi Üniversitesi Fen Bilimleri Dergisi
Bolted joints, which are one of the detachable joining methods, are used extensively. The reliability of bolted joints is extremely important for the strength and life of the system.
Kadir Sarı, Hakan Dilipak
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

How to Improve Usability in Open-Source Software Projects? An Analysis of Evaluation Techniques Through a Multiple Case Study

Informatics
Open-source software has experienced steady growth, driving increased research. However, open-source communities still need standardized processes to ensure software quality, and their characteristics make it challenging to adopt many usability ...
Lucrecia Llerena, John W. Castro, Rosa Llerena, Nancy Rodríguez   +3 more
doaj   +1 more source