Results 81 to 90 of about 1,633,242 (297)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

A Software for Optimum Design of Laterally Loaded Bolted Joints

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi
Bolted joints, which are one of the detachable joining methods, are used extensively. The reliability of bolted joints is extremely important for the strength and life of the system.
Kadir Sarı, Hakan Dilipak
doaj   +1 more source

“ADVANCED COURSE ON SOFTWARE ENGINEERING” AS THE FIRST MODEL FOR TRAINING OF SOFTWARE ENGINEERS

open access: yesÌнформаційні технології в освіті, 2019
Designing a mobile-oriented environment for professional and practical training requires determining the stable (fundamental) and mobile (technological) components of its content and determining the appropriate model for specialist training.
A. Striuk
doaj   +1 more source

Teaching Software Engineering Project Management – A Novel Approach for Software Engineering Programs

open access: yesModern Applied Science, 2011
In response to real and perceived short-comings in the quality and productivity of software engineering practices and projects, professionally-endorsed graduate and post-graduate curriculum guides have been developed to meet technical developments and evolving industry demands.
Caulfield, Craig   +2 more
openaire   +3 more sources

Repository-Based Software Engineering Program: Working Program Management Plan [PDF]

open access: yes
Repository-Based Software Engineering Program (RBSE) is a National Aeronautics and Space Administration (NASA) sponsored program dedicated to introducing and supporting common, effective approaches to software engineering practices.

core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

DYNAMIC TIME WARPING-BASED FUZZY C-MEANS WITH MULTIDIMENSIONAL SCALING FOR TIME SERIES CLUSTERING

open access: yesBarekeng
Weather refers to atmospheric conditions such as temperature, humidity, air pressure, wind speed, and rainfall, all of which influence human activities.
Sri Hidayati   +2 more
doaj   +1 more source

Software engineering and Ada in design [PDF]

open access: yes
Modern software engineering promises significant reductions in software costs and improvements in software quality. The Ada language is the focus for these software methodology and tool improvements.
Oneill, Don
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Review on Program Slicing Techniques towards Program Comprehension Application

open access: yesJournal of Computing Research and Innovation, 2018
Presently, the software system has grown in size. One of the main challenges faced by programmers is to keep up with thousand or million lines of source code that needs to be read and understood.
Rozita Kadar   +2 more
doaj  

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