Results 121 to 130 of about 6,217,824 (300)
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Evolving Pointcut Definition to Get Software Evolution
, 2004 . In this paper, we have briefly analyzed the aspect-oriented approach with respect to the software evolution topic. The aim of this analysis is to highlight the aspect-oriented potentiality for software evolution and its limits.
Sonia Pini +5 more
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A reflective architecture to support dynamic software evolution [PDF]
, 2002 This thesis presents work which is concerned with the run-time evolution of component-based software systems. In particular, the main result of the research presented here is a framework which is used to model and control the architecture of a software ...
Rank, Stephen
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
, 2008 When explaining the true dynamics of legacy systems, we are often short of good metaphors that provoke on the audience the correct understanding of the situation. While war stories are entertaining and fun, the audience often summarizing them as that the
Software Evolution, Chase Workshop
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Software evolution as the key to productivity [PDF]
, 2002 www.iam.unibe.ch/~oscar Abstract. Despite the existence of a seemingly continuous stream of new technologies and methods, software productivity remains universally unimpressive.
Nierstrasz, Oscar, Oscar Nierstrasz
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Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Runtime Evolution of Highly Dynamic Software [PDF]
, 2014 Highly dynamic software systems are applications whose operations are particularly affected by changing requirements and uncertainty in their execution environments. Ideally such systems must evolve while they execute.
Villegas Machado, Norha Milena
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RAMSES: a Reflective Middleware for Software Evolution
, 2004 . Software systems today need to dynamically self-adapt against dynamic requirement changes. In this paper we describe RAMSES a reflective middleware whose aim consists of consistently evolving software systems against runtime changes.
Ahmed Ghoneim +5 more
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