Results 101 to 110 of about 11,335 (296)

Software fault prediction using object-oriented metrics [PDF]

, 2014
Fault-prediction techniques aim to predict the fault prone software modules in order to streamline the effort to be applied in the later phases of software development.
Kumar, L
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

OPTIMIZING SOFTWARE DEFECT PREDICTION USING A HYBRID NEURAL NETWORK WITH WEIGHTED MODIFIED CUCKOO SEARCH [PDF]

Proceedings on Engineering Sciences
Flaws significantly impact the quality, dependability, and maintenance of software. Discovering flaws before they appear in production environments is possible using data mining and classification algorithms.
Devi Priya Gottumukkala , P.V.G.D Prasad Reddy , S. Krishna Rao   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

An empirical investigation into contributory factors of change and fault propensity in large-scale commercial object-oriented software

, 2012
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel UniversityObject-Oriented design and development dominates both commercial and open source software projects.
Gatrell, Matt
core  

Feature selection using the zebra optimization algorithm for software fault prediction: a study on the bughunter dataset

Tạp chí Khoa học và Công nghệ
Software fault prediction focuses on identifying software modules that are most likely to contain faults before the testing stage, helping developers allocate quality assurance resources effectively and improve system reliability.
Ha Thi Minh Phuong, Dao Khanh Duy, Nguyen Do Anh Nhu, Hoang Thi Thanh Ha   +3 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Using faults-slip-through metric as a predictor of fault-proneness

, 2010
The majority of software faults are present in small number of modules, therefore accurate prediction of fault-prone modules helps improve software quality by focusing testing efforts on a subset of modules.
Afzal, Wasif,, Wasif Afzal, Afzal, Wasif
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source