Results 101 to 110 of about 131,864 (294)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Effort-Aware Fault-Proneness Prediction Using Non-API-Based Package-Modularization Metrics
MathematicsSource code complexity of legacy object-oriented (OO) software has a trickle-down effect over the key activities of software development and maintenance. Package-based OO design is widely believed to be an effective modularization. Recently, theories and
Mohsin Shaikh +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Evaluating the effectiveness of decomposed Halstead Metrics in software fault prediction. [PDF]
PeerJ Comput Sci, 2023 Khan B, Nadeem A.
europepmc +1 more source
Software Metrics Evaluation Based on Entropy [PDF]
Software engineering activities in the Industry has come a long way with various improve- ments brought in various stages of the software development life cycle.
Nair, TRG +3 more
core
Reliability Assessment of Legacy Safety-Critical Systems Upgraded with Fault-Tolerant Off-the-Shelf Software [PDF]
, 2012 This paper presents a new way of applying Bayesian assessment to systems, which consist of many components. Full Bayesian inference with such systems is problematic, because it is computationally hard and, far more seriously, one needs to specify a ...
Popov, P. T.
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Predicting software faults in large space systems using machine learning techniques [PDF]
Recently, the use of machine learning (ML) algorithms has proven to be of great practical value in solving a variety of engineering problems including the prediction of failure, fault, and defect-proneness as the space system software becomes complex ...
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source