Results 81 to 90 of about 11,335 (296)

Efficient Simulation of Structural Faults for the Reliability Evaluation at System-Level [PDF]

, 2010
In recent technology nodes, reliability is considered a part of the standard design ¿ow at all levels of embedded system design. While techniques that use only low-level models at gate- and register transfer-level offer high accuracy, they are too ...
Hatami, N., Stefano Di Carlo, Baranowski, R., Wunderlich, H. J., Wunderlich, H.J., Zoellin, C. G., Michael E. Imhof, Hans-Joachim Wunderlich, Di Carlo, Stefano, Nadereh Hatami, Zoellin, C.G., Rafal Baranowski, Kochte, M. A., Imhof, M. E., Imhof, M.E., Paolo Prinetto, Prinetto, Paolo Ernesto, Michael A. Kochte, Kochte, M.A., Christian G. Zoellin   +19 more
core   +1 more source

Search-based approaches to software fault prediction and software testing

, 2009
Software verification and validation activities are essential for software quality but also constitute a large part of software development costs. Therefore efficient and cost-effective software verification and validation activities are both a ...
Afzal, Wasif
core   +1 more source

Semi-Supervised Deep Fuzzy C-Mean Clustering for Software Fault Prediction

IEEE Access, 2018
Software fault prediction is a consequential research area in software quality promise. In this paper, we propose a semi-supervised deep fuzzy C-mean (DFCM) clustering for software fault prediction, which is the cumulation of semi-supervised DFCM ...
Ali Arshad, Saman Riaz, Licheng Jiao, Aparna Murthy   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Achieving Representative Faultloads in Software Fault Injection

, 2011
Given the complexity of modern software systems and its pervasiveness in many aspects of our lives, software faults (i.e., bugs) are a dangerous threat.
Natella, Roberto
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Rough set based gas turbine fault isolation study [PDF]

, 2010
Gas path fault isolation is one of the key techniques in Engine Health Management systems. In order to accomplish gas path fault isolation successfully for a gas turbine engine, both an accurate off-design performance model and an effective fault ...
Wang, Lihui.
core  

Boosting Software Fault Prediction Accuracy with Ensemble Learning

Engineering Proceedings
Software defects are natural quality characteristics of software that are difficult to eliminate completely, even with concerted efforts. In addition to Bayes Net, in this study, C4.5 Decision Tree, Multilayer Perceptron (MLP), and Random Forests (RFs ...
Ashu Mehta, Isha Batra, Anggun Fergina
doaj   +1 more source