Results 51 to 60 of about 397,696 (287)
Discover Civil EngineeringIn this work we develop and validate neural-network (NN) constitutive models for structural steels under monotonic and cyclic loading, using internal-variable inputs to encode path dependence. For monotonic tension at $$200-800^{\circ }C$$ (Kirby-Preston
Stefanos Voulgaris +8 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Deriving Test Suites with the Guaranteed Fault Coverage for Extended Finite State Machines
Моделирование и анализ информационных систем, 2016 Extended Finite State Machines (EFSMs) are widely used when deriving tests for checking functional requirements for software implementations. However, the fault coverage of tests covering appropriate paths, variables, etc.
A. D. Ermakov, N. V. Yevtushenko
doaj +1 more source
Miki: a wiki for synchronous modeling of software requirements [PDF]
, 2011 Eliciting a high quality requirements model that can be traced down to implementations is a challenge. Keeping models updated for evolving software systems is a further challenge.
Petre, Marian +2 more
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Exploring Cortex-M Microarchitectural Side Channel Information Leakage
IEEE Access, 2021 The growing Internet of Things (IoT) market demands side-channel attack resistant, efficient, cryptographic implementations. Such implementations, however, are microarchitecture-specific, and cannot be implemented without an in-depth structural knowledge
Alessandro Barenghi +3 more
doaj +1 more source
Dynamic Information Flow Tracking on Multicores [PDF]
, 2008 Dynamic Information Flow Tracking (DIFT) is a promising technique for detecting software attacks. Due to the computationally intensive nature of the technique, prior efficient implementations [21, 6] rely on specialized hardware support whose only ...
Gupta, Rajiv +3 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source