Results 71 to 80 of about 397,696 (287)

An Experiment in Model Driven Architecture for e-Enterprise Systems [PDF]

, 2002
OMG's Model Driven Architecture demonstrates how a system's specification model can be used within the process of creating supporting software implementations.
Kent, Stuart, Smith, Robert P.
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A Generic Framework for Fourier-Domain Optical Coherence Tomography Imaging: Software Architecture and Hardware Implementations

IEEE Access, 2020
Fourier-domain optical coherence tomography (FD-OCT), including spectral-domain OCT (SD-OCT) and swept-source OCT (SS-OCT), allows the volumetric imaging of the tissue architecture with a faster speed and higher detection sensitivity than does time ...
Yin-Peng Huang, Ting-Yen Tsai, Ting-Hao Chen, Chuan-Bor Chueh, You-Nan Tsai, Yu-Wei Chang, Yi-Chung Wu, Hung-Wen Chen, Meng-Tsan Tsai, Yi-Ping Hung, Hsiang-Chieh Lee   +10 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

An introduction to effective use of enrichment analysis software

Human Genomics, 2010
In recent years, there has been an explosion in the range of software available for annotation enrichment analysis. Three classes of enrichment algorithms and their associated software implementations are introduced here.
Tipney Hannah, Hunter Lawrence
doaj   +1 more source

A validation framework for neuroimaging software: The case of population receptive fields.

PLoS Computational Biology, 2020
Neuroimaging software methods are complex, making it a near certainty that some implementations will contain errors. Modern computational techniques (i.e., public code and data repositories, continuous integration, containerization) enable the ...
Garikoitz Lerma-Usabiaga, Noah Benson, Jonathan Winawer, Brian A Wandell   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Optimized Software Implementation of Keccak, Kyber, and Dilithium on RV{32,64}IM{B}{V}

Transactions on Cryptographic Hardware and Embedded Systems
With the standardization of NIST post-quantum cryptographic (PQC) schemes, optimizing these PQC schemes across various platforms presents significant research value. While most existing software implementation efforts have concentrated on ARM platforms,
Jipeng Zhang, Yuxing Yan, Junhao Huang, Çetin Kaya Koç   +3 more
doaj   +1 more source

PREMIS Events Through an Event-sourced Lens

Code4Lib Journal, 2023
The PREMIS metadata standard is widely adopted in the digital preservation community. Repository software often include fully compliant implementations or assert some level of conformance.
Ross Spencer
doaj  

Methods of Hierarchical Clustering [PDF]

, 2011
We survey agglomerative hierarchical clustering algorithms and discuss efficient implementations that are available in R and other software environments. We look at hierarchical self-organizing maps, and mixture models.
Contreras, Pedro, Murtagh, Fionn
core   +2 more sources