Results 131 to 140 of about 1,789,157 (322)

Robot welding process control development task [PDF]

The completion of, and improvements made to, the software developed during 1990 for program maintenance on the PC and HEURIKON and transfer to the CYRO, and integration of the Rocketdyne vision software with the CYRO is documented.
Romine, Peter L.
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Analyzing Key Features of Open Source Software Survivability with Random Forest

Applied Sciences
Open source software (OSS) projects rely on voluntary contributions, but their long-term survivability depends on sustained community engagement and effective problem-solving.
Sohee Park, Gihwon Kwon
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Commit-Level Software Change Intent Classification Using a Pre-Trained Transformer-Based Code Model

Mathematics
Software evolution is driven by changes made during software development and maintenance. While source control systems effectively manage these changes at the commit level, the intent behind them are often inadequately documented, making understanding ...
Tjaša Heričko, Boštjan Šumak, Sašo Karakatič   +2 more
doaj   +1 more source

Recommended approach to sofware development [PDF]

A set of guideline for an organized, disciplined approach to software development, based on data collected and studied for 46 flight dynamics software development projects.
Church, V., Eslinger, S., Mcgarry, F. E., Merwarth, P., Page, J.   +4 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

GENII (Generation II): The Hanford Environmental Radiation Dosimetry Software System: Volume 3, Code maintenance manual: Hanford Environmental Dosimetry Upgrade Project

, 1988
B.A. Napier, R.A. Peloquin, D.L. Strenge, J.V. Ramsdell   +3 more
openalex   +1 more source

Software maintenance: an approach towards control [PDF]

, 2002
RJ Rob Kusters, F.J. Heemstra
openalex   +1 more source

Software Innovation as Maintenance [PDF]

, 2007
This paper entertains the notion that software maintenance and innovation are more closely related than is commonly accepted. We consider perspectives where innovation projects are understood as attempts to engineer both the social and the technological, where processes of innovation imply the configuring of users, communities, and artifacts through ...
openaire   +2 more sources