Results 111 to 120 of about 770,489 (313)
IEEE AccessThe increasing adoption of AI-powered code generation tools has introduced a critical challenge in software engineering, the potential erosion of developer comprehension of codebases increasingly composed of AI-generated artifacts.
Minav Suresh Patel +3 more
doaj +1 more source
Software Product Support and Maintenance Outsourcing Prepared By EXECUTIVE SUMMARY
, 2008 4 72%: percentage of software product companies who will release a new product each year 4 9 months: s/w product life cycle 4 < 10%: success rate of new products 4 60%: average percentage of maintenance costs to the total cost in the product life ...
Goldstone Technologies +1 more
core
Structural testing techniques for the selective revalidation of software [PDF]
, 1992 The research in this thesis addresses the subject of regression testing. Emphasis is placed on developing a technique for selective revalidation which can be used during software maintenance to analyse and retest only those parts of the program affected ...
Jean Zoren Werner Hartmann +1 more
core
Handling the differential evolution of software artefacts : a framework for consistency management
, 2015 Modern software systems are subject to frequent changes. Different artefacts of a system, such as requirements specifications, design documents and source code, often evolve at different times and become inconsistent with one another.
Balasubramaniam, Dharini +3 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Evaluating software maintenance effort: The COME Matrix
, 2011 If effort estimates are not easily assessed upfront by software maintainers we may have serious problems with large maintenance projects, or when we make repeated maintenance changes to software. This is particularly problematic when inaccurate estimates
June Verner +3 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Using Intentional Source-Code Views to Aid Software Maintenance
, 2003 The conceptual structure of existing software systems is often implicit or non-existing in the source code. We propose the lightweight abstraction of intentional source-code views as a means of making these conceptual structures more explicit.
Kim Mens +6 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source