Results 91 to 100 of about 1,881,120 (294)

Enhancing Bug Report Summaries Through Knowledge-Specific and Contrastive Learning Pre-Training

IEEE Access
Bug reports are crucial in software maintenance, with concise summaries significantly enhancing the efficiency of bug triagers and ultimately contributing to the development of high-quality software products. Contemporary methods for automatic bug report
Yunna Shao, Bangmeng Xiang
doaj   +1 more source

Software maintenance in scientific and engineering environments: An introduction and guide [PDF]

The purpose of software maintenance techniques is addressed. The aims of perfective, adaptive and corrective software maintenance are defined and discussed, especially in the NASA research environment. Areas requiring maintenance, and tools available for
Wright, David
core   +1 more source

Data-Driven Application Maintenance: Views from the Trenches

, 2018
In this paper we present our experience during design, development, and pilot deployments of a data-driven machine learning based application maintenance solution.
Misra, Janardan, Podder, Sanjay, Rawat, Divya, Savagaonkar, Milind, Sengupta, Shubhashis   +4 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Deep Neural Network-Based Severity Prediction of Bug Reports

IEEE Access, 2019
Software maintenance is an essential phase of software development. Developers employ issue tracking systems to collect bugs for software improvement. Users submit bugs through such issue tracking systems and decide the severity of reported bugs.
Waheed Yousuf Ramay, Qasim Umer, Xu Cheng Yin, Chao Zhu, Inam Illahi   +4 more
doaj   +1 more source

Initial flight qualification and operational maintenance of X-29A flight software [PDF]

A discussion is presented of some significant aspects of the initial flight qualification and operational maintenance of the flight control system softward for the X-29A technology demonstrator.
Earls, Michael R., Sitz, Joel R.
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Emotion Based Automated Priority Prediction for Bug Reports

IEEE Access, 2018
Issue tracking systems allow users to report bugs. Bug reports often contain product name, product component, description, and severity. Based on such information, triagers often manually prioritize the bug reports for investigation.
Qasim Umer, Hui Liu, Yasir Sultan
doaj   +1 more source