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Sustaining CyberWater-VisTrails: A Case Study in Software Upgrades and Reengineering

open access: yesInformation
This study focuses on the process of updating and upgrading a large-scale legacy software system to ensure its compatibility with modern computing environments.
Drew Bieger   +6 more
doaj   +1 more source

Maintenance vs. Reengineering Software Systems

open access: yes, 2011
Maintenance and reengineering terms are closely coupled with each other. These terms came from the world of hardware objects. Now these entered the world of software and are well suitable for software systems.
Bakhshsish Singh Gill
core  

A software maintenance method based on the software configuration management discipline [PDF]

open access: yes, 1992
Software maintenance has until recently been the neglected phase in the software engineering process, despite the fact that maintenance of existing software systems may account for over half of all efforts expended by a software organization.
Capretz, Miriam Akemi Manabe
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Prediction of software maintenance costs. [PDF]

open access: yes
This thesis is concerned with predicting the costs of maintaining a computer programprior to the software being developed. The ubiquitous nature of software means thatsoftware maintenance is an important activity, and evidence exists to support ...
Morrison, David J.
core  

Support for an integrated approach to program understanding: an application of software visualisation [PDF]

open access: yes, 1998
Program Comprehension is a key factor in providing effective software maintenance and enabling successful evolution of software systems. The objective of this research is to provide a framework and mechanism to facilitate the understanding of large ...
Chan, Pui Shan
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Enhancing Bug Report Summaries Through Knowledge-Specific and Contrastive Learning Pre-Training

open access: yesIEEE Access
Bug reports are crucial in software maintenance, with concise summaries significantly enhancing the efficiency of bug triagers and ultimately contributing to the development of high-quality software products. Contemporary methods for automatic bug report
Yunna Shao, Bangmeng Xiang
doaj   +1 more source

Who is who in the mailing list? Comparing six disambiguation heuristics to identify multiple addresses of a participant

open access: yes, 2017
Many software projects adopt mailing lists for the communication of developers and users. Researchers have been mining the history of such lists to study communities' behavior, organization, and evolution. A potential threat of this kind of study is that
Steinmacher, I.   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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