Results 71 to 80 of about 770,489 (313)
Software maintenance: The need for standardization [PDF]
Proceedings of the IEEE, 1989 Hardware and software maintenance are contrasted. The key difference between the two-the ease with which software can be changed-leads to the need for managing software change. Standardization of software maintenance is proposed as a method for managing software change.
openaire +2 more sources
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Microservices Evolution Factors: A Multivocal Literature Review
IEEE AccessMicroservices is a software architectural approach based on decomposing systems into small services that are simpler and technology-independent for their development and operation.
Sebastian Pinto-Aguero, Rene Noel
doaj +1 more source
Computing ripple effect for software maintenance
, 2001 Recent software maintenance models have included impact analysis and accounting for ripple effect as one of their stages. This paper describes and explains the reformulation of Yau and Collofello's ripple-effect algorithm and its validity within the ...
Black, S.E.
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
IEEE AccessSoftware quality and long-term maintainability represent fundamental challenges in modern software engineering. Among the critical factors that affect these attributes are code smells, indicators of structural deficiencies in the source code, which ...
Ronald Henry Diaz Arrieta +3 more
doaj +1 more source
Software maintenance: an approach towards control
Proceedings IEEE International Conference on Software Maintenance. ICSM 2001, 2002 In this paper the software maintenance process will be looked at in more detail from a control point of view. From this it can be seen that in most situations no proper control mechanisms exist and that even the basic requirements for control are not fulfilled. The remainder of the paper will be devoted towards describing a basic approach that provides
Rob J. Kusters, Fred J. Heemstra
openaire +5 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
ADKT: a support tool for reducing architectural knowledge evaporation in software projects
DynaDefining software architecture is a complex task that demands technical expertise and business knowledge. Design decisions drive architectural structures throughout development and maintenance.
Santiago Hyun-Dorado +3 more
doaj +1 more source
Software maintenance by program transformation in a wide spectrum language [PDF]
, 1994 This thesis addresses the software maintenance problem of extracting high-level designs from code. The investigated solution is to use a mathematically-based formal program transformation system.
Bull, Tim
core