Results 61 to 70 of about 1,881,120 (294)
Measuring the software process and product: Lessons learned in the SEL [PDF]
, 1985 The software development process and product can and should be measured. The software measurement process at the Software Engineering Laboratory (SEL) has taught a major lesson: develop a goal-driven paradigm (also characterized as a goal/question/metric
Basili, V. R.
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Multilingual Source Code Analysis: A Systematic Literature Review
IEEE Access, 2017 Contemporary software applications are developed using cross-language artifacts, which are interdependent with each other. The source code analysis of these applications requires the extraction and examination of artifacts, which are build using multiple
Zaigham Mushtaq +2 more
doaj +1 more source
Software maintenance: an approach towards control
Proceedings IEEE International Conference on Software Maintenance. ICSM 2001, 2002 In this paper the software maintenance process will be looked at in more detail from a control point of view. From this it can be seen that in most situations no proper control mechanisms exist and that even the basic requirements for control are not fulfilled. The remainder of the paper will be devoted towards describing a basic approach that provides
Kusters, R.J., Heemstra, F.J.
openaire +5 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Empirical Study on the Evolution of Developer Social Networks
IEEE Access, 2018 Software development is incredibly complex. Specifically, open-source software (OSS) development requires developers to collaborate with each other to conduct their work.
Mohamed Abdelrahman Aljemabi +1 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Improving Maintenance-Consistency Prediction During Code Clone Creation
IEEE Access, 2020 Developers frequently introduce code clones into software through the copy-and-paste operations during the software development phase in order to shorten development time.
Fanlong Zhang +2 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source