Results 51 to 60 of about 1,881,120 (294)

A Systematic Literature Review on Software Maintenance for Cyber-Physical Systems

IEEE Access, 2021
Cyber-physical systems (CPS) are widely used in almost every sector of our modern life. They are also changing the way how systems are designed and maintained as CPS represent a combination of hardware and software components.
Nadhira Khezami, Marouane Kessentini, Thiago Do N. Ferreira   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Design and Implementation of JPEG 2000 Image Compression using FPGA

Journal of Engineering and Sustainable Development, 2006
This paper investigates the use of a Field Programmable Gate Array (FPGA Xilinx Virtex-II) to perform hardware implementation for low speed part of JPEG2000 to achieve a real time JPEG2000 system.
Munther N. B. Al-Tikriti, Dhafer R. Z. Al-Rawi, Ienas F. Y. Iskander   +2 more
doaj  

Code comprehension as a distributed construction of meanings [PDF]

Biuletyn Wojskowej Akademii Technicznej, 2019
Code comprehension, a sub-domain of reverse engineering and software maintenance, does not provide useful explanation of common situations where developers, distributed and isolated from each other in time and space, come to a similar understanding of a ...
Piotr Cofta
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

ViViMZheimer a slice based end to end model for Alzheimer’s disease diagnosis from 3D MRI

Scientific Reports
Slice-based models have been widely applied in Alzheimer’s disease (AD) identification tasks due to their reduced parameter count and fast inference speed.
Juan Zhou, Jiahui Wan, Xia Chen, Xiong Li, Zejiu Wu, Zhiwei Zhang, Chengjie Zhang   +6 more
doaj   +1 more source

Code Drones

, 2016
We propose and explore a new paradigm called Code Drones in which every software artifact such as a class is an intelligent and socially active entity. In this paradigm, humanized artifacts take the lead and choreograph (socially, in collaboration with ...
Acharya, Mithun P., Dagnino, Aldo, Kraft, Nicholas A., Parnin, Chris, Qu, Xiao   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Effort-Aware Fault-Proneness Prediction Using Non-API-Based Package-Modularization Metrics

Mathematics
Source code complexity of legacy object-oriented (OO) software has a trickle-down effect over the key activities of software development and maintenance. Package-based OO design is widely believed to be an effective modularization. Recently, theories and
Mohsin Shaikh, Irfan Tunio, Jawad Khan, Younhyun Jung   +3 more
doaj   +1 more source