Results 41 to 50 of about 3,483,326 (328)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

Mining Task-Specific Lines of Code Counters

open access: yesIEEE Access, 2023
Context: Lines of code (LOC) is a fundamental software code measure that is widely used as a proxy for software development effort or as a normalization factor in many other software-related measures (e.g., defect density).
Miroslaw Ochodek   +3 more
doaj   +1 more source

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn   +4 more
wiley   +1 more source

Search Model of the Region With the Maximum Coverage Value Based on Trajectory Data

open access: yesIEEE Access, 2019
The wide application of mobile terminals has given rise to a large number of trajectory data. These data record spatio-temporal mobility of mobile objects and have important value for urban planning, traffic congestion detection, and other applications ...
Zhongwei Yue   +4 more
doaj   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li   +9 more
wiley   +1 more source

Refractive Index Sensor Based on the Fano Resonance in Metal–Insulator–Metal Waveguides Coupled with a Whistle-Shaped Cavity

open access: yesMicromachines, 2022
A plasmonic refractive index sensor based on surface plasmon polaritons (SPPs) that consist of metal–insulator–metal (MIM) waveguides and a whistle-shaped cavity is proposed.
Bo Li   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Liquid Level Measurement Model Outside of Closed Containers Based on Continuous Sound Wave Amplitude

open access: yesSensors, 2018
This research put forward an exogenous liquid level measurement method based on continuous sound wave amplitude. The distribution of round piston transducers in the sound field of a metal solid was analyzed by building 15 Multi-Gaussian Beam ...
Yanjun Zhang   +5 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Balanced Objective-Quantifiers Method (BOQM) For Software Intensive Organizations Strategies [PDF]

open access: yes, 2008
Spanish university facilitates a method to link the strategic management with Software and Process improvement based on measurement. The method uses the process philosophy to build measurable information in Indicators templates (Based on ISO/IEC 15939 ...
De-Amescua Seco, Antonio
core   +1 more source

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