Results 41 to 50 of about 3,483,326 (328)
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Mining Task-Specific Lines of Code Counters
Context: Lines of code (LOC) is a fundamental software code measure that is widely used as a proxy for software development effort or as a normalization factor in many other software-related measures (e.g., defect density).
Miroslaw Ochodek +3 more
doaj +1 more source
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn +4 more
wiley +1 more source
Search Model of the Region With the Maximum Coverage Value Based on Trajectory Data
The wide application of mobile terminals has given rise to a large number of trajectory data. These data record spatio-temporal mobility of mobile objects and have important value for urban planning, traffic congestion detection, and other applications ...
Zhongwei Yue +4 more
doaj +1 more source
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source
A plasmonic refractive index sensor based on surface plasmon polaritons (SPPs) that consist of metal–insulator–metal (MIM) waveguides and a whistle-shaped cavity is proposed.
Bo Li +8 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Liquid Level Measurement Model Outside of Closed Containers Based on Continuous Sound Wave Amplitude
This research put forward an exogenous liquid level measurement method based on continuous sound wave amplitude. The distribution of round piston transducers in the sound field of a metal solid was analyzed by building 15 Multi-Gaussian Beam ...
Yanjun Zhang +5 more
doaj +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Balanced Objective-Quantifiers Method (BOQM) For Software Intensive Organizations Strategies [PDF]
Spanish university facilitates a method to link the strategic management with Software and Process improvement based on measurement. The method uses the process philosophy to build measurable information in Indicators templates (Based on ISO/IEC 15939 ...
De-Amescua Seco, Antonio
core +1 more source

