Results 71 to 80 of about 3,526,971 (274)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

SDN as Active Measurement Infrastructure [PDF]

, 2017
Active measurements are integral to the operation and management of networks, and invaluable to supporting empirical network research. Unfortunately, it is often cost-prohibitive and logistically difficult to widely deploy measurement nodes, especially ...
Beverly, Robert, Rye, Erik
core   +1 more source

A new digital image correlation software for displacements field measurement in structural applications [PDF]

, 2017
Recently, there has been a growing interest in studying non-contact techniques for strain and displacement measurement. Within photogrammetry, Digital Image Correlation (DIC) has received particular attention thanks to the recent advances in the field of
Belloni, Valeria, Crespi, Mattia Giovanni, Di Rita, Martina, Mattei, Domitilla, Nascetti, Andrea, Nistico', Nicola, Ravanelli, Roberta   +6 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A Liquid Level Measurement Technique Outside a Sealed Metal Container Based on Ultrasonic Impedance and Echo Energy

Sensors, 2017
The proposed method for measuring the liquid level focuses on the ultrasonic impedance and echo energy inside a metal wall, to which the sensor is attached directly, not on ultrasonic waves that penetrate the gas–liquid medium of a container. Firstly, by
Bin Zhang, Yue-Juan Wei, Wen-Yi Liu, Yan-Jun Zhang, Zong Yao, Li-Hui Zhao, Ji-Jun Xiong   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Systems Engineering Leading Indicators Guide, Version 1.0 [PDF]

, 2013
The Systems Engineering Leading Indicators guide set reflects the initial subset of possible indicators that were considered to be the highest priority for evaluating effectiveness before the fact.
International Council on Systems Engineering, Lean Advancement Initiative, Practical Software and Systems Measurement, Systems Engineering Advancement Research Initiative   +3 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Sign Language Recognition Based on CNN-BiLSTM Using RF Signals

IEEE Access
As the number of individuals with speech and hearing impairments continues to grow, the demand for sign language recognition systems is increasing. Furthermore, most radio frequency-based gesture recognition systems have primarily focused on simple ...
Yajun Zhang, Yuankang Wang, Feng Li, Weiqian Yu, Congcong Wang, Ying Jiang   +5 more
doaj   +1 more source

Annotated bibliography of Software Engineering Laboratory literature [PDF]

An annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory is given. More than 100 publications are summarized.
Morusiewicz, Linda, Valett, Jon D.
core   +4 more sources