Results 101 to 110 of about 4,534,833 (370)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Software Measurement and Defect Prediction with Depress Extensible Framework

open access: yesFoundations of Computing and Decision Sciences, 2014
Context. Software data collection precedes analysis which, in turn, requires data science related skills. Software defect prediction is hardly used in industrial projects as a quality assurance and cost reduction mean. Objectives.
Madeyski Lech, Majchrzak Marek
doaj   +1 more source

Pragmatic quality metrics for evolutionary software development models [PDF]

open access: yes
Due to the large number of product, project, and people parameters which impact large custom software development efforts, measurement of software product quality is a complex undertaking.
Royce, Walker
core   +1 more source

Towards a metrics suite for object oriented design

open access: yesConference on Object-Oriented Programming Systems, Languages, and Applications, 2017
While software metrics are a generally desirable feature in the software management functions of project planning and project evaluation, they are of especial importance with a new technology such as the object-oriented approach.
Shyam R. Chidamber, C. Kemerer
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

landscapemetrics : an open‐source R tool to calculate landscape metrics

open access: yesEcography, 2019
Quantifying landscape characteristics and linking them to ecological processes is one of the central goals of landscape ecology. Landscape metrics are a widely used tool for the analysis of patch‐based, discrete land‐cover classes.
M. Hesselbarth   +4 more
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

AUTOMATING SOFTWARE DEVELOPMENT PRODUCTIVITY METRICS [PDF]

open access: yes, 1990
Measurement of software development productivity is needed in order to control software costs, but it is discouragingly labor-intensive and expensive. Computer aided software engineering (CASE) technologies -- especially object-oriented, integrated CASE -
Banker, Rajiv D.   +4 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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