Results 81 to 90 of about 3,835,935 (170)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Assessing Evolution of Microservices Using Static Analysis
Applied SciencesMicroservices have gained widespread adoption in enterprise software systems because they encapsulate the expertise of specific organizational subunits. This approach offers valuable insights into internal processes and communication channels.
Amr S. Abdelfattah +5 more
doaj +1 more source
Dataset of open-source software developers labeled by their experience level in the project and their associated software metrics. [PDF]
Data Brief, 2023 Perez Q, Urtado C, Vauttier S.
europepmc +1 more source
A software testing estimation and process control model [PDF]
, 1998 The control of the testing process and estimation of the resource required to perform testing is key to delivering a software product of target quality on budget.
Archibald, Colin J.
core
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Automated software quality visualisation using fuzzy logic techniques [PDF]
, 2007 In the past decade there has been a concerted effort by the software industry to improve the quality of its products. This has led to the inception of various techniques with which to control and measure the process involved in software development ...
Senior, James +5 more
core
An empirical investigation of an object-oriented software system [PDF]
, 2000 This is the post print version of the article. The official published version can be obtained from the link below.This paper describes an empirical investigation into an industrial object-oriented (OO) system comprised of 133,000 lines of C++. The system
Cartwright, MH, Shepperd, M
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source