Results 71 to 80 of about 3,835,935 (170)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
An Information Theoretic Evaluation of Software Metrics for Object Lifetime Prediction [PDF]
, 2008 Accurate object lifetime prediction can be exploited by allocators to improve the performance of generational garbage collection by placing immortal or long-lived objects directly into immortal or old generations.
Watson, Ian +6 more
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Development time estimation using software metrics
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 The article describes investigation of the ability to use software metrics for development time estimation of existing software product as well as investigation of the ability to predict development time of new software product at the design stage ...
Y. V. Liah
doaj
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Компютерні системи та інформаційні технологіїMobile applications have long become an integral part of everyday life and have gained popularity among ordinary users, small companies, and large enterprises. However, this is a completely separate area of software.
Lidiia MAKAROVA, Maxim TATARENKO
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Application of Blockchain Technologies in Verification of Software Metrics
Applied SciencesWhen creating software, it is important to focus not only on the functionality requested by users but also on ensuring that the software exhibits qualities such as maintainability, testability, comprehensibility, and reusability.
Jovan Milutinović +4 more
doaj +1 more source
Examining the Capacity of Text Mining and Software Metrics in Vulnerability Prediction. [PDF]
Entropy (Basel), 2022 Kalouptsoglou I +4 more
europepmc +1 more source