Results 71 to 80 of about 997,849 (284)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Applying Software Metrics to evaluate Business Process Models

open access: yesCLEI Electronic Journal, 2006
In this paper, we define a set of metrics for the evaluation of conceptual models of business processes. The proposal supposes the adaptation and extension of the FMESP framework (Framework for the Modeling and Evaluation of Software Processes).
Elvira Rolón   +3 more
doaj   +1 more source

An Approach to Evaluate the Complexity of Block-Based Software Product

open access: yesInformatics in Education, 2020
Computer programming skills have been growing as a professional competence also to unqualified end-users who need to develop software in their professional practice. Quality evaluation models of end-user-developed products are still scarce. In this paper,
Ilenia FRONZA, Luis CORRAL, Claus PAHL
doaj   +1 more source

Using a Combination of Measurement Tools to Extract Metrics from Open Source Projects [PDF]

open access: yes, 2016
Software measurement can play a major role in ensuring the quality and reliability of software products. The measurement activities require appropriate tools to collect relevant metric data.
Awang Abu Bakar, Normi   +1 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Assessment of the total software product development time [PDF]

open access: yesВојно дело, 2016
The main motive of this paper on software engineering is to confront the engineering approach to the software development with the artistic one. Software engineering is the youngest engineering discipline and, as such, it still involves a high degree of ...
Živadinović Jovan   +2 more
doaj   +1 more source

Bayesian inference for a software reliability model using metrics information. [PDF]

open access: yes, 2001
In this paper, we are concerned with predicting the number of faults N and the time to next failure of a piece of software. Information in the form of software metrics data is used to estimate the prior distribution of N via a Poisson regression model ...
Rodríguez Bernal, María Teresa   +1 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A neural net-based approach to software metrics [PDF]

open access: yes
Software metrics provide an effective method for characterizing software. Metrics have traditionally been composed through the definition of an equation.
Boetticher, G.   +2 more
core   +1 more source

Software Metrics and Dashboard [PDF]

open access: yes, 2015
Software metrics are a critical tool which provide continuous insight to products and processes and help build reliable software in mission critical environments.
Aguiar, Saulo   +4 more
core  

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