Results 211 to 220 of about 4,534,833 (370)

Building a continuous benchmarking ecosystem in bioinformatics. [PDF]

PLoS Comput Biol
Mallona I, Soneson C, Carrillo B, Lütge A, Incicau D, Gerber R, Sonrel A, Robinson MD.   +7 more
europepmc   +1 more source

A Study on Software Complexity Measure Based on Hybrid Module Metrics

, 1992
Jung-Mo Yoon
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

An integrated graph neural network model for joint software defect prediction and code quality assessment. [PDF]

Sci Rep
Dai P, Zhu H, Wu J, He H.
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Metrics in Large-Scale Agile Software Development: A Multivocal Literature Review

Renato Menezes, Marcelo Marinho, Suzana Sampaio   +2 more
openalex   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Impact of Algorithmic Modifications Targeting the Meal Period and the Management of Hypoglycemia and Hyperglycemia in Adult Persons With Type 1 Diabetes Using Closed-Loop Insulin Delivery: A Two-Step Observational Report. [PDF]

J Diabetes Sci Technol
Benhamou PY, Vesin A, Reynaud L, Chatel B.   +3 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

TPCpp-10M: Simulated proton-proton collisions in a time projection chamber for AI foundation models. [PDF]

Data Brief
Li S, Huang Y, Park D, Luo X, Yu H, Go Y, Pinkenburg C, Lin Y, Yoo S, Osborn J, Roland C, Huang J, Ren Y.   +12 more
europepmc   +1 more source