Results 31 to 40 of about 346,980 (259)

An Evaluation of Software Measurement Processes in Pakistani Software Industry

open access: yesIEEE Access, 2018
Implementing a successful measurement process is a challenging task. Most measurement studies report measurement models, experiences, and lessons learned based on pilot projects or case studies in a limited scope to overcome specific challenges.
Touseef Tahir   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Actionable Software Metrics [PDF]

open access: yesProceedings of the Evaluation and Assessment in Software Engineering, 2020
Background: Practitioners would like to take action based on software metrics, as long as they find them reliable. Existing literature explores how metrics can be made reliable, but remains unclear if there are other conditions necessary for a metric to be actionable. Context & Method: In the context of a European H2020 Project, we conducted a multiple
Ram, Prabhat   +8 more
openaire   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

FABASOFT BEST PRACTICES AND TEST METRICS MODEL

open access: yesJournal of Information and Organizational Sciences, 2007
Software companies have to face serious problems about how to measure the progress of test activities and quality of software products in order to estimate test completion criteria, and if the shipment milestone will be reached on time.
Nadica Hrgarek
doaj  

Logical Framework of Information Technology: Systematization of Software Development Research

open access: yesTelfor Journal, 2022
This article aims to present a comprehensive Logical Framework for Information Technology (IT) Research, specifically for developing customized IT applications or software.
D. Sa’adillah Maylawati   +1 more
doaj   +1 more source

Software Product Quality Metrics: A Systematic Mapping Study

open access: yesIEEE Access, 2021
In the current competitive world, producing quality products has become a prominent factor to succeed in business. In this respect, defining and following the software product quality metrics (SPQM) to detect the current quality situation and continuous ...
Fatima Nur Colakoglu   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Improving Software Defect Prediction by Aggregated Change Metrics

open access: yesIEEE Access, 2021
To ensure the delivery of high quality software, it is necessary to ensure that all of its artifacts function properly, which is usually done by performing appropriate tests with limited resources.
Lucija Sikic   +3 more
doaj   +1 more source

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