Results 121 to 130 of about 543,049 (269)
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Empipe3D™ User’s Manual Version 4.0 -- UNIX
, 1997 Empipe3D is a powerful and friendly software system for automated electromagnetic (EM) design optimization, driving the 3D field solvers Ansoft HFSS and HP HFSS.
Bandler, John W. +3 more
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Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Thermal food processing computation software
, 2011 The objective of this research consisted of developing the two following thermal food processing software: “F-CALC” is software developed to carry out thermal process calculations based on the well-known Ball's formula method, and “OPT-PROx” is software ...
Abakarov, Alik
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EnergiesAirborne Wind Energy (AWE) systems offer benefits such as high altitude access to stronger and more stable winds, reduced environmental impact, and cost effective infrastructure.
Yanjun Lv +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
On The Behaviour Of Constrained Optimization Methods When Lagrange Multipliers Do Not Exist
, 2015 Sequential optimality conditions are related to stopping criteria for nonlinear programming algorithms. Local minimizers of continuous optimization problems satisfy these conditions without constraint qualifications. It is interesting to discover whether
Andreani R. +3 more
core +1 more source
High-viscosity microenvironment inhibits endocytosis of drug-loaded nanoparticles in cancer cells
Nano ResearchDrug-loaded nanoparticles (DLNPs) enhance intracellular drug accumulation through endocytosis and are widely used in chemotherapy research. Despite progress, the therapeutic efficacy of DLNPs remains limited due to the complexity of the in vivo ...
Guanlin Zhou, Chengwei Wu, Wei Zhang
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Decomposition-Based Method for Sparse Semidefinite Relaxations of Polynomial Optimization Problems [PDF]
We consider polynomial optimization problems pervaded by a sparsity pattern. It has been shown in [1, 2] that the optimal solution of a polynomial programming problem with structured sparsity can be computed by solving a series of semidefinite ...
Berc Rustem +2 more
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