Results 131 to 140 of about 6,479,069 (356)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

SRS BUILDER 1.0: An Upper Type CASE Tool For Requirement Specification [PDF]

open access: yesarXiv, 2011
Software (SW) development is a labor intensive activity. Modern software projects generally have to deal with producing and managing large and complex software products. Developing such software has become an extremely challenging job not only because of inherent complexity, but also mainly for economic constraints unlike time, quality, maintainability
arxiv  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

A multiprocess quality model: identification of of key processes in the integration approach [PDF]

open access: yes, 2012
In this paper we investigate the use of multiprocess quality model in the adoption of process improvement frameworks. We analyze an improvement effort based on multiple process quality models adoption.
Abd. Rahman, Aedah   +2 more
core  

New Failure Rate Model for Iterative Software Development Life Cycle Process [PDF]

open access: yesarXiv, 2019
Software reliability models are one of the most generally used mathematical tool for estimation of reliability, failure rate and number of remaining faults in the software. Existing software reliability models are designed to follow waterfall software development life cycle process.
arxiv  

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