Key role for inhibins in effective T cell activation, migration and Th17 differentiation
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco+5 more
wiley +1 more source
Topic modeling-based prediction of software defects and root cause using BERTopic, and multioutput classifier. [PDF]
Gottumukkala DP, P V G D PR, Rao SK.
europepmc +1 more source
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado+4 more
wiley +1 more source
Applying a system dynamics approach for decision-making in software testing projects. [PDF]
Li W, Fang CC.
europepmc +1 more source
Single-click automated fractal analysis for dental radiographs: a comparative evaluation with classic ImageJ method. [PDF]
Balel Y, Sağtaş K.
europepmc +1 more source
Development and implementation of cancer clinical trial patient screening using an electronic medical record-integrated trial matching system. [PDF]
Bui N+13 more
europepmc +1 more source
Efficient self-healing framework for smart distribution networks. [PDF]
Meteab F, Tousi B, Omran M.
europepmc +1 more source
Operating parameter optimization and experiment of spiral outer grooved wheel seed metering device based on discrete element method. [PDF]
Zhang T, Tang X, Dai C, Ren G.
europepmc +1 more source
Investigation of an EPID-based dose verification system for patient-specific quality assurance in a harmony device. [PDF]
Yoo D+7 more
europepmc +1 more source