Results 51 to 60 of about 6,479,069 (356)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Teaching software process modeling [PDF]

open access: yes2013 35th International Conference on Software Engineering (ICSE), 2013
Most university curricula consider software processes to be on the fringes of software engineering (SE). Students are told there exists a plethora of software processes ranging from RUP over V-shaped processes to agile methods. Furthermore, the usual students' programming tasks are of a size that either one student or a small group of students can ...
Marco Kuhrmann   +2 more
openaire   +4 more sources

What Should a Good Software Requirements Specification Include? Results of a Survey

open access: yesFoundations of Computing and Decision Sciences, 2023
Software requirements specification is an important foundation of the software development process. It documents the requirements, expectations, and restrictions for a system to be developed.
Rączkowska-Gzowska Karolina   +1 more
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Process Mining Framework for Software Processes

open access: yes, 2007
Software development processes are often not explicitly modelled and sometimes even chaotic. In order to keep track of the involved documents and files, engineers use software configuration management systems. Along the way, those systems collect and store information on the software development process itself.
Vladimir Rubin   +5 more
openaire   +4 more sources

Software-Engineering Process Simulation (SEPS) model [PDF]

open access: yes, 1992
The Software Engineering Process Simulation (SEPS) model is described which was developed at JPL. SEPS is a dynamic simulation model of the software project development process.
Abdel-Hamid, T.   +2 more
core   +1 more source

Automating the Object-Oriented Software Development Process: Workshop Report [PDF]

open access: yes, 1998
Cost-effective realization of robust, adaptable and reusable software systems demands efficient and effective management of the overall software production process.
Aksit, Mehmet, Tekinerdogan, Bedir
core   +3 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Comparison of Gaussian process modeling software [PDF]

open access: yes, 2016
Gaussian process fitting, or kriging, is often used to create a model from a set of data. Many available software packages do this, but we show that very different results can be obtained from different packages even when using the same data and model ...
Ankenman, Bruce E.   +2 more
core   +2 more sources

Using grounded theory to understand software process improvement: A study of Irish software product companies [PDF]

open access: yes, 2007
Software Process Improvement (SPI) aims to understand the software process as it is used within an organisation and thus drive the implementation of changes to that process to achieve specific goals such as increasing development speed, achieving higher ...
Blaxter   +22 more
core   +1 more source

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