Results 71 to 80 of about 2,745,230 (267)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

ProcessM: Intelligent Process Mining software

open access: yesSoftwareX
Contemporary software guides and executes various business processes, such as production, delivery of goods, sales, and official procedures. However, due to software flexibility, unforeseen circumstances, and exceptional conditions, processes may not ...
Tomasz P. Pawlak, Jędrzej Potoniec
doaj   +1 more source

Aplicação e análise de processo de desenvolvimento de software: um estudo de caso no GPES-IFPB

open access: yesRevista Principia, 2018
The Software Engineering Research Group from the Federal Institute of Paraiba is developing a research to identify and publicize on the web the best practices in software development processes, seeking to propagate their use among professionals and ...
Samyra Lara Ferreira Almeida   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Software Package STATISTICA and Educational Process

open access: yesSHS Web of Conferences, 2016
The paper describes the main aspects of application of the software package STATISTICA in the educational process. Technologies of data mining which can be useful for students researches have been considered.
Demidova Liliya   +7 more
doaj   +1 more source

Software development processes

open access: yesComput. Sci. J. Moldova, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Process For Performance Evaluation Of Real-Time Systems [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2003
Real-time developers and engineers must not only meet the system functional requirements, but also the stringent timing requirements. One of the critical decisions leading to meeting these timing requirements is the selection of an operating system under
Andrew J. Kornecki, Eric Sorton
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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