Results 251 to 260 of about 2,065,794 (327)

Structured Process Informed by Data, Evidence and Research (SPIDER) framework: Eight legs of success for running projects in primary care practices. [PDF]

Can Fam Physician
Greiver M, Dahrouge S, Manca DP, Singer AG, Jean-Xavier C, Kosowan L, Pathiraja H, Grandy M, Lussier MT, Aubrey-Bassler K, O'Brien T, Authier M, Dev R, Garies S.   +13 more
europepmc   +1 more source

Lingma SWE-GPT: An Open Development-Process-Centric Language Model for Automated Software Improvement [PDF]

Yingwei Ma, Rongyu Cao, Yongchang Cao, Yue Zhang, Jue Chen, Y. Liu, Yuchen Liu, Binhua Li, Fei Huang, Yongbin Li   +9 more
openalex   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Using FRAM visualisations in quality improvement projects: identifying and testing strategies to improve anticoagulant use in the perioperative process. [PDF]

Int J Qual Health Care
Luijcks NM, Visser A, Dongelmans DA, van Dongen DMG, de Graaf EL, Groeneweg J, van der Laan MJ, Marang-van de Mheen PJ, FIAF Study Group .   +8 more
europepmc   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

The intervention effect of structured martial arts games on behavioral impairments and motor functions in children with autism spectrum disorder. [PDF]

Front Psychol
Fu X, Shi P.
europepmc   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

IFEM model framework for the accreditation of training sites for emergency medicine specialists. [PDF]

Int J Emerg Med
Singer A, Chu S, Venkataraman A, Jouriles N, Cevik AA, Kwan J.   +5 more
europepmc   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source