Results 31 to 40 of about 652,827 (236)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
A cloud software life cycle process (CSLCP) model
Ain Shams Engineering Journal, 2021 Small to medium-sized enterprises take advantage of the strengths and opportunities of cloud computing. These enterprises require a well-defined software process model to produce reliable and quality cloud software, given their limited resources ...
Amira A. Alshazly +3 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Change-Oriented Open Source Software Process Simulation
IEEE Access, 2018 The goal of our research is to find better ways for assessing the impact of changes to the software projects and the cost-effectiveness of process improvement strategies.
Xuan Zhang, Xu Wang, Yanni Kang
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Software Testing in Small IT Companies: A (not only) South African Problem
South African Computer Journal, 2011 Small software companies make for the majority of software companies around the world, but their software development processes are often not as clearly defined and structured as in their larger counterparts. Especially the test process is often the most
Stefan Gruner, Johan van Zyl
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Social networks in software process improvement [PDF]
Journal of Software Maintenance and Evolution: Research and Practice, 2009 AbstractSoftware process improvement in small organisation is often problematic and communication and knowledge sharing is more informal. To improve software processes we need to understand how they communicate and share knowledge. In this article have studied the company SmallSoft through action research.
Nielsen, Peter Axel, Tjørnehøj, Gitte
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Revista Científica de Ingeniería Industrial, 2014 En el presente artículo se fundamenta la utilidad de realizar un diagnóstico al iniciar la mejora de procesos de software, haciendo uso de los factores críticos de éxito para identificar las fortalezas y las debilidades de acometer el cambio.
Yaimí Trujillo-Casañola +5 more
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