Results 51 to 60 of about 2,196,372 (288)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Software Testing in Small IT Companies: A (not only) South African Problem
South African Computer Journal, 2011 Small software companies make for the majority of software companies around the world, but their software development processes are often not as clearly defined and structured as in their larger counterparts. Especially the test process is often the most
Stefan Gruner, Johan van Zyl
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Revista Científica de Ingeniería Industrial, 2014 En el presente artículo se fundamenta la utilidad de realizar un diagnóstico al iniciar la mejora de procesos de software, haciendo uso de los factores críticos de éxito para identificar las fortalezas y las debilidades de acometer el cambio.
Yaimí Trujillo-Casañola +5 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mapeo sistemático sobre la evaluación de la agilidad en organizaciones de desarrollo de software
Iteckne, 2019 Los enfoques ágiles de desarrollo de software proporcionan grandes beneficios para las organizaciones, sin embargo su implementación está sujeta a muchos desafíos. Para las organizaciones es importante conocer el nivel de agilidad alcanzado y las brechas
Wilson Alfredo Ortega-Ordóñez +2 more
doaj +1 more source
Integrating automated support for a software management cycle into the TAME system [PDF]
, 1989 Software managers are interested in the quantitative management of software quality, cost and progress. An integrated software management methodology, which can be applied throughout the software life cycle for any number purposes, is required. The TAME (
Basili, Victor R., Sunazuka, Toshihiko
core +1 more source
The influence of managerial experience and style on software development process [PDF]
, 2008 This paper presents the results of a study of how software process and software process improvement is applied in actual practice in the software industry using the indigenous Irish software product industry as a test-bed.
Coleman, Gerry, O'Connor, Rory
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source