Results 41 to 50 of about 1,924,275 (351)

Software Process Improvement by Managing Situational Method Engineering Knowledge [PDF]

open access: yesJournal of Universal Computer Science
Organizational processes have been recognized as valuable knowledge assets. Situational Method Engineering (SME) processes are particularly valuable as they are used for engineering other processes: SME processes help construct bespoke Software ...
Razieh Dehghani, Raman Ramsin
doaj   +3 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Software process improvement in graduate software engineering programs [PDF]

open access: yes, 2015
At the École de technologie supérieure (ÉTS), software process improvement (SPI) is taught in lecture format and with a 10-week implementation project in an organization by teams of students of the graduate software engineering curriculum.
Laporte, Claude, O'Connor, Rory
core   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Method to construct a taxonomy: basic structure to risks in software outsourcing

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2012
This paper proposes a risk taxonomy that focuses on software acquisition environment. According to this, the goal of this approach is to define an ordered risk classification structure related with to software acquisition.
Gloria Piedad Gasca Hurtado   +1 more
doaj   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Organisational readiness and software process improvement [PDF]

open access: yes, 2007
The Capability Maturity Model Integration (CMMI) is a structured representation of software development processes that can support an organisation's software process improvement (SPI) strategies.
Niazi, M, Wilson, D, Zowghi, D
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Change-Oriented Open Source Software Process Simulation

open access: yesIEEE Access, 2018
The goal of our research is to find better ways for assessing the impact of changes to the software projects and the cost-effectiveness of process improvement strategies.
Xuan Zhang, Xu Wang, Yanni Kang
doaj   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

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