Results 171 to 180 of about 2,245,735 (312)

An Improved Differential Evolution Solution for Software Project Scheduling Problem.

ScientificWorldJournal, 2015
Biju AC, Victoire TA, Mohanasundaram K.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Scrum Game: An Agile Software Management Game

For the past few years, in their attempt to avoid the heavyweight bureaucracy of traditional project management methods such as the Waterfall model, companies have started incorporating agile methods (e.g.
Gkritsi, Aikaterini
core  

Free Open Source Software for Business Intelligence

, 2010
Free Open Source Software (FOSS) has recently grown, becoming a significant part of the IT market. We use the word “FOSS” to refer to software under a license which grants the right to access the source code and use, study, and change the software.
BALABAN, DAVID
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

LCR-modules: a collection of workflows for cancer genome analysis. [PDF]

Bioinformatics
Dreval K, Hilton LK, Grande BM, Banco G, Coyle KM, Cruz M, Gillis S, Klossok L, Pararajalingam P, Rushton CK, Shaalan H, Thomas N, Winata H, Wong J, Yiu J, Steidl C, Scott DW, Morin RD.   +17 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Open Source Software Development Patterns and License Terms [PDF]

This paper examines the choice of license terms along the development of a piece of software. Three licenses are compared, the proprietary one, the Berkeley Software Distribution, and the General Public License.
Alexandre Gaudeul
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Ten simple rules for executing an inherited research plan in computational biology. [PDF]

PLoS Comput Biol
Javaheri Tehrani S, Gossmann TI.
europepmc   +1 more source