Results 161 to 170 of about 14,528,728 (295)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Do papers tell the whole story? A benchmark and framework for uncovering hidden implementation gaps in bioinformatics. [PDF]

Brief Bioinform
Xu T, Zhu X, Lai X, Lian X, Dang S, Cheng H, Wang J.   +6 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Human cardiac measurements with diamond magnetometers. [PDF]

Sci Adv
Omar M, Benke M, Zhang S, Zhang J, Wang Y, Kuebler M, Sharbati P, Rahimpour A, Gück A, Kapitonova M, Kadam D, René Izquierdo Geiser C, Haller J, Trautmann A, Jag-Lauber K, Rölver R, Nguyen TD, Gizzi L, Schweizer M, Abdelsayed M, Wickenbrock I, Edmonds AM, Markham M, Koss PA, Schnell O, Hofmann UG, Ball T, Beck J, Budker D, Wrachtrup J, Wickenbrock A.   +30 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Perioperative antithrombotic management in degenerative spine surgery: a multicenter cohort of 767 consecutive patients. [PDF]

Front Med (Lausanne)
Corazzelli G, Corvino S, Rios DL, Gentile D, Di Domenico C, Corazzelli F, De Rosa G, Fiore F, Germano C, Filippelli M, Colella N, Ricciardi F, D'Elia A, Leonetti S, Sacco M, Meglio V, Pizzuti V, Di Russo P, Gorgoglione N, Petrella G, Mastantuoni C, Scala MR, de Angelis M, De Bellis A, Cioffi V, Aloj F, Sigona L, Bocchetti A, Di Colandrea S, Coscia G, Passavanti MB, Cuomo A, De Marinis P, Tocchetti CG, de Divitiis O, Mormile M, Cirillo P, Catapano G, de Falco R, Paolini S, Esposito V, Innocenzi G.   +41 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Shiny binary modeling platform: a reproducibility-oriented software platform for structured binary modeling with integrated interpretation, validation support, model comparison, and archive export. [PDF]

Front Pharmacol
Du H, Huang X, Liu T, Dolkun A.
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Correction: From architectural complexity to minimalist optimization: refining microscopic tea disease detection via Opti-YOLOv11n. [PDF]

Front Plant Sci
Hu C, Liu Z, Li Q, Yan Y, Liu F, He Y, Li X, Chen H, Yang C, Li J, Wei M, Liang Y, Yuan X.   +12 more
europepmc   +1 more source