Results 51 to 60 of about 4,881,863 (349)

Integrate the GM(1,1) and Verhulst models to predict software stage effort [PDF]

open access: yes, 2009
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2009 IEEE. Personal use of this material is permitted.
MacDonell, S   +4 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Estimating software project effort using analogies [PDF]

open access: yes, 1997
Accurate project effort prediction is an important goal for the software engineering community. To date most work has focused upon building algorithmic models of effort, for example COCOMO. These can be calibrated to local environments. We describe an
Schofield, C, Shepperd, MJ
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

A Novel Risk Metric for Staff Turnover in a Software Project Based on Information Entropy

open access: yesEntropy, 2015
Staff turnover in a software project is a significant risk that can result in project failure. Despite the urgency of this issue, however, relevant studies are limited and are mostly qualitative; quantitative studies are extremely rare.
Rong Jiang
doaj   +1 more source

A Software Projects Crest and Trough in Pakistan: A Management Spectrum

open access: yesSukkur IBA Journal of Computing and Mathematical Sciences, 2023
Software industry has become as popular factor in the progress triumph of every country. Software project management techniques are significantly applicable in the development cycle of software projects.
Salwa iqbal   +2 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Using the PMO to enforce and standardize the attention of software project managers to needs of software project teams

open access: yesInternational Journal of Information Systems and Project Management, 2023
Software project teams (SPTs) are critical stakeholders. Their contribution in successful delivery of software projects is unquestionable. However, the empirical evidence of their importance seems to exist on paper only, as software project managers ...
Robert Hans, Ernest Mnkandla
doaj  

Software management tools: Lessons learned from use [PDF]

open access: yes, 1985
Experience in inserting software project planning tools into more than 100 projects producing mission critical software are discussed. The problems the software project manager faces are listed along with methods and tools available to handle them ...
Knight, J.   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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