Results 41 to 50 of about 1,981,488 (283)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Robust Control of Autonomous Underwater Vehicles Using Delta-Sigma-Based 1-bit Controllers
IEEE Access, 2023 Autonomous underwater vehicles (AUVs) are robots capable of operating underwater without the need for human operators. Nonetheless, there is the essential requirement of remote operation capability in case of exceptional situations, such as the encounter
Chathura Wanigasekara +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Jurnal IUS, 2016 The higher the age and quality enhancement technology, the higher the level of knowledge of technology, with a number of associations hackers and expert coding for trying to duplicate a video game that has been produced by the creators in the form of ...
Robby Akhmad Surya Dilaga
doaj +1 more source
Asymmetry of Caddo Ceramics from the Washington Square Mound Site: An Exploratory Analysis [PDF]
, 2017 While pursuing a study of 3D geometric morphometrics for ceramic burial vessels that often articulate with the Native American Graves Protection and Repatriation Act (NAGPRA) from the ancestral Caddo region, there have been no shortage of potentially ...
Selden, Robert Z., Jr.
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Copyright Protection For Software [PDF]
, 1998 The United States blazed the trail in giving copyright protection for software. Until just recently, many other countries favored sui generis protection for software, but that argument was finally settled in GATT/TRIPs and last December\u27s World ...
Oman, Ralph
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Control system for a superconducting rectifier using a microcomputer [PDF]
, 1981 Within the scope of a research program of superconducting rectifiers software is being developed to take care of the control of such systems. The hard-ware architecture which interferes with the in and output signals is based on a LSI-11/2 microprocessor
Caspari, Meindert +4 more
core +4 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source