Results 101 to 110 of about 5,112,197 (346)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

National Wildlife Refuges and Intensive Management in Alaska: Another Case for Preemption [PDF]

open access: yes, 2010
Developing high quality software is difficult. Traditional software engineering methods emphasizes on structured and linear workflow of activities methods that have been criticized due to their rigid and inflexible nature.
Joly, Julie Lurman
core   +1 more source

A Conceptual UX-aware Model of Requirements

open access: yes, 2016
User eXperience (UX) is becoming increasingly important for success of software products. Yet, many companies still face various challenges in their work with UX.
Feldt, Robert   +3 more
core   +2 more sources

Assessing the impact of software quality models in healthcare software systems. [PDF]

open access: yesHealth Syst (Basingstoke), 2023
Ronchieri E, Canaparo M.
europepmc   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Usability: key characteristic of software quality / Применяемость: ключевая характеристика качества программного обеспечения / Upotrebljivost kao ključna karakteristika kvaliteta softvera

open access: yesVojnotehnički Glasnik, 2017
The paper emphasizes the importance of software usability as a key quality characteristic of software during its use. At the beginning of the paper, a retrospective of formal definitions of usability is given in order to show the evolution of views on
Nebojša D. Đorđević
doaj   +1 more source

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