Results 101 to 110 of about 5,226,528 (353)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Cost-benefit modelling for reliability growth
, 2003 Decisions during the reliability growth development process of engineering equipment involve trade-offs between cost and risk. However slight, there exists a chance an item of equipment will not function as planned during its specified life. Consequently
Lesley Walls +3 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Evaluating the Impact of Prediction Techniques: Software Reliability Perspective
, 2021 Kavita Sahu +3 more
semanticscholar +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Software reliability growth modeling for agile software development
International Journal of Applied Mathematics and Computer Science, 2017 The frequent incremental release of software in agile development impacts the overall reliability of the product. In this paper, we propose a generic software reliability model for the agile process, taking permanent and transient faults into ...
Rawat Shubham, Goyal Nupur, Ram Mangey
doaj +1 more source
Predicting Software Reliability in Softwarized Networks
CoRRProviding high quality software and evaluating the software reliability in softwarized networks are crucial for vendors and customers. These networks rely on open source code, which are sensitive to contain high number of bugs. Both, the knowledge about the code of previous releases as well as the bug history of the particular project can be used to ...
Hasan Yagiz Özkan +3 more
openaire +2 more sources
BAYESIAN INFERENCE FOR A SOFTWARE RELIABILITY MODEL USING METRICS INFORMATION. [PDF]
In this paper, we are concerned with predicting the number of faults N and the time to next failure of a piece of software. Information in the form of software metrics data is used to estimate the prior distribution of N via a Poisson regression model ...
M.T. Rodríguez Bernal, Michael P. Wiper
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source